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Useful Stats: NIH SBIR/STTR application success rates & trends, FY 2012-2021

Friday, July 22, 2022

In fiscal year 2021, the nationwide success rate of applicants for National Institutes of Health (NIH) Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I awards decreased slightly from FY 2020. This continued a downward trend over recent years. The success rate for NIH SBIR/STTR Phase I was nearly 13 percent (647 of 5,132 approved) in FY 2021, a decrease from nearly 14 percent (636 of 4,684 approved) in FY 2020 and from nearly 16 percent for all proposals submitted over the past decade.

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Report: NIH SBIR/STTR program supported 99 drugs, numerous successful companies over 25 years

Thursday, February 17, 2022

The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs of the National Institutes of Health (NIH) supported the development of 99 drugs from 1996-2020 — a total that includes 16 percent of all such treatments that made a “significant” advance over available medicines.

  • Read more about Report: NIH SBIR/STTR program supported 99 drugs, numerous successful companies over 25 years

Useful Stats: Measuring NIH SBIR/STTR Awards by State, 2019

Thursday, April 30, 2020

In this week’s edition of Useful Stats, we take a look at NIH’s SBIR/STTR program by state, including the success rate of applications, the share SBIR awards make up of NIH funding to for-profit companies by state, and the total number of awards by state. It should be noted that SSTI was able to prepare this information because of the excellent transparency of information that NIH offers on its website, a model that should be replicated by other federal agencies.

  • Read more about Useful Stats: Measuring NIH SBIR/STTR Awards by State, 2019

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Recent news from the SSTI Digest

Universities as architects of regional innovation ecosystems

Wednesday, July 8, 2026
Ask most university leaders how their institution contributes to the regional economy and the answer is likely to include research expenditures, patents, startups, and jobs. Those measures remain important, but they overlook one of the university's most valuable contributions. In today’s economy, where innovation, talent, and technology shape how regions grow, universities are helping communities adapt, connect, and compete.
regionalism
innovation

TBED programs succeed by engaging with local communities

Wednesday, July 8, 2026
When a new TBED project comes to town, the TBED practitioners inside know the long-term benefits of technology-based economic development: they can see and understand their progress in building a strong economic foundation for their host region. But for community-based and workforce development organizations and K-12 education systems in the surrounding area, the TBED project might appear to be an opaque operation that operates independently of its neighbors.
tbed

What to expect when you’re expecting (investment returns)

Wednesday, July 8, 2026
Following SSTI’s recent look at the timing and type of exits, we continue our look at investment activity to characterize returns on investments so that TBED investors can more accurately project and adjust program parameters to support long-term sustainability. Accurate data on venture capital investment returns and fund performance on private investment vehicles is not readily or consistently available. Anecdotal stories  and the occasional press release on a major transaction exist, but VC exits are often done quietly. As such, parties interested in understanding performance outcomes must rely on focused reports and other aggregate data. 
investing
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