Massachusetts Gov. Deval Patrick's secretary of Housing and Economic Development, Daniel O'Connell, resigned for personal reasons and was replaced by Greg Bialecki, an undersecretary who has been responsible for business development

Dyan Brasington, former president of the Technology Council of Maryland, is the new director of economic and workforce development at Towson University.

Greater Baltimore Technology Council executive director Penny Lewandowski is leaving at the end of May to join the Edward Lowe Foundation in Detroit. Assistant director Steve Kovak has been named her successor.

Johns Hopkins University has named Jill Tarzian Sorenson to serve as associate provost and director of the Office of Licensing and Technology Development.

The nation's most significant source of funding for life science research, the National Institutes of Health, announced two sweeping changes last week that could dramatically alter biotechnology commercialization. The first policy change addresses known and potential conflicts of interest by NIH employees, while the second encourages all NIH-funded research to be released publicly within 12 months of final publication.

The Technology Innovation Program (TIP) in the National Institute of Standards and Technology is using its FY09 award competition to support high-risk, high-reward research in civil infrastructure and manufacturing. The program has $25 million available to support as many as 25 new awards. TIP is open to individual small-sized or medium-sized businesses or to joint ventures that also may include institutions of higher education, nonprofit research organizations and national laboratories.

With a $25 million funding opportunity currently on the streets for manufacturing and infrastructure research projects, the Technology Innovation Program (TIP) has added three more locations and dates for proposers' conferences next week. The free public meetings will provide general information regarding TIP, guidance on preparing proposals, and the opportunity for questions and answers.

John Reardon will be new Charles County Economic Development Department chief in Maryland, effective in December.

Maryland has a new program to provide loans to early stage technology-oriented companies that are affiliated with the incubation network, Governor Robert Ehrlich announced earlier this month. The $500,000 Working Capital Loan Fund, administered by the Maryland Technology Development Corporation (TEDCO), will offer low-interest, flexible term loans of between $15,000 and $50,000 to companies in underserved parts of Maryland.

Phillip Singerman resigned as executive director of the Maryland Technology Development Corp.. Renee Winsky will serve as interim executive director until a permanent replacement is named.

The Maryland Department of Business and Economic Development appointed Benjamin Wu as the assistant secretary for the Capital Region and senior advisor for technology policy.

Supporters of NIST's Advanced Technology Program (ATP) have weathered years of attempts by members of the House and the Bush Administration to eliminate the program, but this may be the biggest hurdle yet: The Senate Appropriations Committee approved language calling for the program's termination as part of the Department of Commerce fiscal year 2007 appropriations. The first of only two ATP-related sentences included in the Senate Committee report 109-580 accompanying H.R.

For the third year, the Maryland Technology Development Corporation (TEDCO) has been named the nations most active source of early-stage or angel capital. TEDCO leads the list of the 100 top venture capital firms, based on the quarterly MoneyTree survey published by PriceWaterhouseCoopers, Thomson Venture Economics and the National Venture Capital Association (NVCA). The 2005 list appears in the July issue of Entrepreneur magazine.

C. Robert Eaton is resigning as president of MdBio, effective March 31, 2007, to pursue other opportunities in the private sector.