As the National Nanotechnology Initiative (NNI) prepares to enter its third decade, it is seeking public input on what that future should look like. NNI is drafting its 2021 strategic plan and has several big changes under consideration, including a reorganization and shifts in research and commercialization priorities. For instance, as nanotechnology matures and reaches broader applications, so too do questions around “responsible development,” including environmental, health and safety considerations, according to NNI. Workforce and education needs grow as well as nanotechnology moves from lab to market.