SSTI’s new analysis of NIH data reveals the agency’s external R&D spending per award has been essentially treading water for the past 25 years in terms of real dollars—rising just 4% since FY 2000 when adjusted for inflation. This slow growth comes despite the crucial role NIH funding plays in technology-based economic development (TBED) policies across many states, particularly in the biomedical and life sciences. However, NIH funding remains a major economic driver as the world’s largest funder of biomedical and behavioral research, having generated nearly $2.50 of economic activity for every dollar spent in FY 2023, according to NIH estimates. While these awards support innovation, academic research, and regional economies, their purchasing power has eroded over time, barely keeping pace with inflation.