For three decades, the SSTI Digest has been the source for news, insights, and analysis about technology-based economic development. We bring together stories on federal and state policy, funding opportunities, program models, and research that matter to people working to strengthen regional innovation economies.

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Advanced chemistry R&D is target of new $123M fund

A new $123 million fund will work to recruit up to 45 chemistry researchers and their teams to Indiana universities over the next five years, betting on the premise that building research talent is a prerequisite for the state’s broader life sciences ambitions. “The researchers recruited through the fund will bring together an unmatched cluster of multi-disciplinary expertise to develop platform technologies necessary to enable the reshoring of life science manufacturing and work to tackle industry-informed grand challenges,” stated BioCrossroads’ CEO and President, Vince Wong.  

Innovation Advocacy Council visits the Hill on your behalf

“We few, we happy few” shouldn’t have been so bloody few if Shakespeare’s Henry V were honest 400+ years ago. Flash forward, and a merry band of brothers and sisters represented the TBED community well as they visited DC’s Capitol Hill this week to remind Congressional offices of the importance of several federal programs for funding strategic regional innovation initiatives. And it was nothing like Henry V’s Battle of Agincourt. In truth, regional innovation is and always has been a nonpartisan issue, but there are other pressures afoot to capture Congress’s attention and purse strings. 

Legislative & Federal News

ARPA-H cancels relationships with ARPANet-H partners 

In a Feb. 20 email, ARPA-H announced the end of its contracts with Houston-based Customer Experience and Boston-based Investor Catalyst to manage the hub-and-spoke approach to connecting research institutions, investors, and the health industry market. The agency promised in its email, however, that it was retaining its hub-and-spoke structure for service delivery and would have offices in Dallas and Boston, yet still establishing “a more direct connection from you, the spokes, to the hubs and ARPA-H.”

DOE Science Office reorganized (again) 

Member News for March 26, 2026

The Central Indiana Corporate Partnership (CICP) is now doing business as the CEOs of Indiana Corporate Partnership. The CICP brand will soon feature the new identity, including marketing materials and a redesigned logo. The legal name, Central Indiana Corporate Partnership, will remain unchanged. 

New federal data shows that Case Western Reserve University is the nation’s fastest-growing top-tier research institution. This year, the university’s R&D spending surged 37.5%. It is opening a new $300 million science hub later this year. 

Tech Hub News for March 26,2026

Regional innovation systems across the country can learn from the journeys of the EDA's designated Tech Hubs, regardless of your region’s competitive advantage. The twelve hubs continue to make progress, with consortia launching new programs and advancing key initiatives. The following highlights recent news from a selection of hubs. SSTI supports the Tech Hub community through its Technology-Based Economic Development Community of Practice. 

 

State News for March 26, 2026

Mar 26, 2026 

On March 17, Indiana Gov. Mike Braun revealed a new tax credit initiative aimed at creating 100,000 high-wage agriculture and life sciences jobs over the next decade, with the Indiana Economic Development Corporation (IEDC) committing $1 billion in tax credits toward those jobs. The initiative stems from an executive order from Braun last year directing Indiana’s 15 economic regions to submit formal growth plans to boost economies, per capita income, and educational attainment. To qualify for the credit, jobs will have to pay 125% of a county’s median annual wage. 

Webinar: A Conversation with the 2026 global entrepreneurship research award winners, Al Link and Don Siegel on Technology Transfer and Academic Entrepreneurship

April 8, 2:00 p.m. EDT Free  

Two of the more influential and most deserving American academic researchers in university innovation policy are being recognized this year for their decades of contributions by a prestigious global award. SSTI is excited to host this special conversation with both recipients, names known well by many, to remind us all and to help make more of the TBED community aware of their important work.  

SSTI is pleased to host Albert N. Link and Donald S. Siegel, recipients of the 2026 Global Award for Entrepreneurship Research, for a discussion of their work on technology transfer and innovative entrepreneurship. 

Useful Stats: How has the relationship between GDP and R&D changed since the 1950s?

Total research and experimental development (R&D) performed in the U.S. reached nearly $1 trillion of expenditures in 2024, reveals new data from the National Center for Science and Engineering Statistics (NCSES). This represents a 6% increase over the prior year, a 101% increase in the past 10 years, and a nearly 16,000% increase in the past 70 years.

Adjusted for inflation, total R&D expenditures, relative to their 2024 values, have increased more modestly but still reflect impressive growth: 3% since 2023; 56% in the 10 years since 2015; and approximately 1,670% in the 70 years since 1955.

Figure 1 below includes two line charts, each with a line for billions of current and constant (2017) USD: GDP on the left and R&D expenditures on the right. Periods of recession are highlighted in grey for applicable years. Note that each chart has a different y-axis. 

With OZ expansion looming, research shows program has little net jobs impact

When the Opportunity Zone program was authorized by Congress in 2017, there was high hope that it would give a significant boost to the employment rates of those living in the poorest areas of our cities. Unfortunately, a new research paper adds to the growing findings of the program’s shortcomings and disappointing outcomes, just as the next race to establish new OZ designations is set to begin.   

Data centers may be inevitable, but state and local resistance is growing

People in the U.S. may be in favor of the using internet, social media, and artificial intelligence, but they are increasingly skeptical of and concerned about the data centers that make all these things possible. Common themes of their skepticism were recently expressed by data center opponents in Michigan who “fear lost farmland and destroyed habitat, noise pollution from thousands of humming servers, strain on the electric grid and higher bills as utilities spend mightily on infrastructure to power the facilities, and strain on rivers and aquifers amid data centers’ use of water to cool servers.” Michiganders are not alone. 

TBED Works: Rev1’s eye for potential and support helps launch biotech company

TBED-driven investors keep an eye out for existing intellectual property that could, with the right management team, develop into a local company with a market-ready product. Rev1, a nonprofit venture development organization that manages several for-profit investment funds, partners with Nationwide Children’s Hospital to support the commercialization of promising research that advances the hospital’s mission. For about six years, the Rev1 team monitored Nationwide’s research on the challenge of the bacterial biofilm, a catalyst for inflammation and exacerbations in chronic respiratory disease. When the time was right, they played a critical role in founding the company, Clarametyx Biosciences, in Columbus, Ohio. 

Recent Research: National industrial policy to reshore US manufacturing can yield positive local effects

Three academic researchers estimate that the localized job creation impacts resulting from the CHIPS and Science Act already have had a net gain of 12% in the affected counties. The direct jobs in the semiconductor sector alone are 15,000-16,000 short-term positions. With the high-paying nature of jobs in the field, researchers Bilge Erten, Joseph E. Stiglitz, and Eric Verhoogen estimate that, as a spillover effect, 15,000 to 30,000 additional indirect jobs have been created in related sectors.