SSTI Digest

Illinois lawmakers passed landmark legislation  to regulate America’s leading AI companies. While the recently passed Senate Bill (SB) 315, the Artificial Intelligence Safety Measures Act, mirrors existing provisions in enacted legislation in California and New York, which require frontier AI companies like OpenAI and Anthropic to create, publish and annually update plans to address severe or catastrophic risks from their AI models; the new measure would also mandate annual independent third-party audits of such AI companies on safety issues, which would be a first for any AI legislation in the U.S. Gov. JB Pritzker has indicated he intends to sign it.  

California officials want residents to help shape policies regarding artificial intelligence through a statewide digital democracy initiative called “Engaged California.” Under the initiative, the state will collect feedback on how AI is impacting Californians’ work, the state’s economy, and the future. Residents’ input would help to inform decision-making, policies, and ultimately assist officials in developing a more inclusive and equitable AI action plan for government leaders.  

Gov. Gavin Newsom announced the launch of California’s first solar-covered canal, a pilot project that seeks to generate clean electricity, keep water from evaporating before it ever reaches a farm or a faucet, and, if scaled further, help strengthen the state’s water infrastructure to withstand a hotter, drier future.  

The momentum building in the 21 “Building Better Regions” (BBR) projects is growing, and RTI, the leader of the BBBRC Community of Practice, and SSTI are seeing positive impacts and approaches to collaborative regional innovation that could benefit other practitioners and TBED stakeholders if made aware of the success.

National VC investment over the past five years has seen significant swings, first driven by pandemic impacts and rebounds, then by the rocket ride of AI. According to PitchBook data, national VC activity below $100 million declined from nearly 10,500 deals in 2020 to just under 8,200 in 2025, a 22% drop. Over the same period, the total capital invested increased by just over $5 billion (6%). The trend of more funding into fewer deals is highlighted by the median deal size more than doubling to over $4 million (Fig 1). These macro trends are important as they set the stage for what is happening at the state level. 

The new year begins with a layer of both fiscal and political uncertainty. For at least 18 states, it will be a year of change in political leadership. After several years of continuous revenue growth, states are crafting their Fiscal Year (FY) 2027 budgets amid slower growth, rising costs, and heightened unease. At the same time, the 2026 gubernatorial campaign season also begins in earnest. More than three dozen governorships are on the November ballot, and at least 18 states (see map below) expect to elect a new governor due to an incumbent either being term-limited or choosing not to run for re-election.

The proposed Biomanufacturing Excellence Act of 2025 would establish a single National Biopharmaceutical Manufacturing Center of Excellence within the U.S. Department of Commerce’s National Institute of Standards and Technology (NIST). H.R. 6089 was introduced by Rep. Chrissy Houlahan (D-PA) with bipartisan cosponsors and paired with a Senate companion bill (S. 3188) led by Senators Chris Coons (D-DE) and Ted Budd (R-NC). It authorizes $120 million in FY 2026 for NIST to conduct a competitive process to select one non-federal entity to build and operate the center. Eligible applicants include public-private partnerships, institutions of higher education, and multi-institution consortia. Because only a single awardee will be chosen, the proposed legislation likely sets up what is likely to be a stiff competition among many states which have made life sciences and manufacturing key elements of their innovation strategies.

This week’s 2025 off-year elections resulted in two new governors, solidified legislative Democratic majorities in New Jersey and Virginia, and the approval of significant ballot measures in California and Texas. While the gubernatorial campaigns centered on affordability and tapped into an electorate’s concerns about state and national economies, they also kick off speculation on the 2026 midterms.  

As states strive to strengthen their science, technology, innovation, and entrepreneurship programs during an uncertain federal funding period, many are developing strategic plans that provide a roadmap for doing so. SSTI has recently seen examples of plans from West Virginia, Arizona, and California.

California Gov. Gavin Newsom recently released the state’s new  Jobs First Economic Blueprint, a comprehensive plan and major statewide economic initiative designed to spur sustainable economic growth on a region-by-region basis, to reflect the diverse character of the many parts and peoples of California. 

Made up of 10 strategic industry sectors, including clean energy, advanced manufacturing, healthcare, agriculture and agtech, technology, and innovation, the California Jobs First Economic Blueprint will guide the state’s investments into the policies and programs that seek to create more jobs, faster and to ensure that the investments are sustainable and inclusive (including the regions’ rural, disadvantaged, or underserved communities).

As such, the plan provides for:

FYI This Week, a science policy newsletter from the American Institute of Physics, reported in their November 25 article Commerce aims to commit CHIPS money before Trump returns that “Commerce Secretary Gina Raimondo said … she is trying to allocate all the semiconductor manufacturing and research funds appropriated by the CHIPS and Science Act before President Joe Biden leaves office." Since Raimondo made that statement, the U.S. Department of Commerce (DoC) has announced the following CHIPS and Science Act Awards:

Gov. Gavin Newson of California announced that the state is approved for $1.1 billion of funding from the State Small Business Credit Initiative (SSBCI), which represents the largest funding amount that has been approved in the SSBCI program. The funding will support the launch of a new $200 million venture capital program and and will help fund small business credit support programs. The allocated amount will be equally split between the California Infrastructure and Economic Development Bank (IBank) and the California Pollution Control Financing Authority.