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The Institutes and Centers of the National Institutes of Health receive an increase of $301 million in budget authority for a new total of $47.216 billion in FY 2026, a figure that stands in sharp contradiction to the severe cuts recommended in the Administration’s request. Additionally, ARPA-H is to receive $1.5 billion.
Of the nearly $7 billion in the FY 2026 appropriations bill working its way through Congress for the Department of Housing and Urban Development, 51.7% is slated for “economic development initiatives (EDIs)” designated by members of Congress outside of any competitive process or assessment of need. The Community Development Block Grant program captures most of the rest of the funding at $3.3 billion. Separately, the Native American/Indian community block grant program is to receive $100 million.
With report language in the final budget package for FY 2026, Congress continues to thwart some of the administration’s efforts to shrink government operations and spending by fiat. In the Department of Transportation’s section, projects cannot be terminated without following established federal financial assistance regulations and established agency protocols. DOT must also inform Congress of how it will address the substantial backlog of projects, particularly of “awarded but not obligated competitive grant and community project funding.” This includes previously passed congressionally directed spending projects (earmarks) that the agency has not awarded, which is certainly one way to antagonize appropriators. Additionally, any “reprogramming requests must be submitted to the Committees on Appropriations no later than June 30, 2026.”
The breakthrough launch of ChatGPT in November 2022 sparked widespread questions about artificial intelligence and the future of work. How would generative AI reshape jobs and industries? Would certain roles become obsolete? How should education and training programs prepare workers for an AI-integrated workplace? To understand AI’s actual labor market impact, researchers examined unemployment patterns and hiring trends in AI-exposed occupations between 2022 and 2024 in a new study. Their findings suggest that labor market shifts in those fields began earlier than ChatGPT’s high-profile arrival might suggest.
Innovation districts have become a central tool in contemporary economic development, promoted for their ability to revitalize underused urban areas, attract high-growth firms, and strengthen regional competitiveness. Influenced by early work from Bruce Katz and colleagues at the Brookings Institution, many districts were intentionally located in formerly industrial or disinvested neighborhoods and initially delivered clear economic gains.
Most startups begin rich in vision but poor in financial support. Some founders have been known to go to great lengths to advance what they know to be worthwhile project. Asklepios BioPharmaceutical (AskBio), established in 2001, survived its earliest days with the help of bake sales held by families whose children had muscular dystrophy and believed in the startup's potential to develop treatments for the condition. When Lindy Biosciences was founded in 2017, its founder was not financially compensated for her time. However, after early assistance from the North Carolina Biotechnology Center (NCBiotech), both companies now have market values measured in billions of dollars.
The Financial Services and General Government appropriations bill for FY 2026 passed the House of Representatives yesterday and now moves to the Senate where passage is also expected. The bill sets spending levels for several agencies supporting regional innovation, economic development, and investment. Foremost are the Treasury and Small Business Administration; selected highlights are provided below.
All too often, jobseekers and employers seem to exist in non-compatible realities. While jobseekers flood the job market with descriptions of their generalized skills in communication, leadership, and problem-solving to fill various roles in different sectors, employers are looking for the more specific skills that will get the job done, say the authors of a report from the Wharton School and Accenture. And they propose that AI is accelerating this shift from a role-based economy to a skills-based economy.
With 2025 behind us, and some time for the data to stabilize, we can look back at VC activity and try to understand what it means for TBED efforts going forward. The VC storyline of 2025 should be familiar to anyone who has been following investment news. Record funding rounds, huge amounts of capital deployed, questions of an AI bubble. Where amongst the big flashy lights of AI mega-deals do we find the subtlety and nuance that informs TBED investor activity and policy? Looking closely at historical trends and segmenting the data by deal size highlights what most companies seeking funding face and points to potential outcomes for 2026.
Richard Bendis has significant experience building biotech clusters in formerly “flyover” regions (e.g., places that lack the infrastructure to support tech-based entrepreneurs and companies). Around 2009-2010, he was giving a presentation at the National Academy of Sciences in Washington, D.C., on how to build these regions around an industry-driven private-public partnership. After the talk, someone from Johns Hopkins approached him and said they had been trying—with little success—to build a biotech cluster in Maryland. They asked him to come to Montgomery County, Maryland, the epicenter of the region's life sciences industry.
Higher Education Research and Development (HERD) expenditures grew in every state between Fiscal years (FYs) 2010 and 2024, rising 92% nationally over the 15-year period. Adjusted for inflation, five states and Puerto Rico instead experienced a real decline in HERD expenditures. Despite this broad growth, HERD expenditures remain highly concentrated, with five states having accounted for nearly 40% of all higher education R&D expenditures nationwide in FY 2024.
Leadership in Congress has developed a plan to move all the FY 2026 budget appropriations bills before the end of the month. First up in a “compromise” package that includes, among other agencies, appropriations for the Departments of Commerce, NASA and the National Science Foundation. 1/8/26 UPDATE: The House passed the package on the afternoon of Jan 8. Instructions accompanying the bill provide insights into how Congress would like to see the agencies use the funding. Selected highlights for the TBED community are provided below.
