Pennsylvania Gov. Ed Rendell is set to release his fiscal year 2006-07 budget request later this week, which is expected to significantly redesign the state's investment in biotechnology and life science research, according to materials released by the governor's office.

Dr. Melvyn Schiavelli, senior program officer for the Harrisburg Polytechnic Development Corporation, has been named acting president and CEO, succeeding Dr. Charles Clevenger.

Many areas of the country are experiencing a brain drain, an outmigration of recent college graduates leading to a decline in the available labor pool of entry level workers, young entrepreneurs and future civic leaders. A new initiative, however, hopes to reverse that trend in Northeastern Pennsylvania by strengthening the social, networking and professional relationships among young skilled workers in the Wilkes-Barre region.

Secretary of the Pennsylvania Department of Community and Economic Development for the past five-and-a-half years, Sam McCullough is resigning effective October 25.

Greater Philadelphia First (GPF) and the Science Center, a consortium of 34 regional academic and scientific institutions, have established a major new joint initiative designed to make it easier for science and technology entrepreneurs to start, grow and expand their businesses. Modeled on UCSD CONNECT in San Diego, CONNECT Greater Philadelphia will assist entrepreneurs by linking them with needed business, academic and other resources.

The Ben Franklin Technology PArtners of Central and Northern Pennsylvania promoted Stephen Brawley to serve as president and CEO.

Alan Brown was named executive director of the Pennsylvania NanoMaterials Commercialization Center, a newly formed economic development initiative.

Jeanne B. Berdik has announced her retirement as Vice President of Workforce Education and Development at the Pittsburgh Technology Council and Catalyst Connection. See next article for job posting.

SSTI Affiliate, the Pittsburgh Technology Council (PTC) seeks candidates to become the organization's Vice President for Workforce Education and Development. The senior-level position is responsible for the management of all Catalyst Connection and Pittsburgh Technology Council education programs and services and IT workforce development and recruitment strategies.

Kevin Harter is leaving his position as president of the Central Pennsylvania Technology Council to become senior vice president of the new Life Sciences Greenhouse of Central Pennsylvania.

Pennsylvania Governor Mark Schweiker has been named President and CEO of the Greater Philadelphia Chamber of Commerce. The Governor will assume his new position on Feb. 1.

Fritz Bittenbender will become president of the Pennsylvania Biotechnology Association in December.

Innovation Philadelphia, the public-private partnership dedicated to enhancing the global innovation economy of Philadelphia, has unveiled the first Innovation and Entrepreneurial Index, a comprehensive study examining where Philadelphia stands in relation to key competitors in the Innovation Economy.

Dennis Yablonsky, who has been serving as CEO for both the Pittsburgh Digital Greenhouse and the Pittsburgh Life Sciences Greenhouse for most of the past year, has decided to focus exclusively on the biotech initiative. His replacement as president and CEO at the Pittsburgh Digital Greenhouse is David Ruppersberger.

To shed light on the strengths and weaknesses of the region's biotechnology cluster, Carnegie Mellon University's Center for Economic Development (CED) has published A Biotechnology Action Plan for Southwestern Pennsylvania. The CED report says the Pittsburgh biotechnology cluster largely depends on the amount of available venture capital and the development of new technologies and that total funding levels must be increased to continue biotech development.

Don Smith has been appointed Vice President for Economic Development at the new Mellon Pitt Carnegie Corporation. MPC, a joint venture of the University of Pittsburgh and Carnegie Mellon University, is intended to coordinate the economic development and tech commercialization activities of both schools.