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Useful Stats: NIH SBIR/STTR application success rates & trends, FY 2012-2021

Friday, July 22, 2022

In fiscal year 2021, the nationwide success rate of applicants for National Institutes of Health (NIH) Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) Phase I awards decreased slightly from FY 2020. This continued a downward trend over recent years. The success rate for NIH SBIR/STTR Phase I was nearly 13 percent (647 of 5,132 approved) in FY 2021, a decrease from nearly 14 percent (636 of 4,684 approved) in FY 2020 and from nearly 16 percent for all proposals submitted over the past decade.

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Report: NIH SBIR/STTR program supported 99 drugs, numerous successful companies over 25 years

Thursday, February 17, 2022

The Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs of the National Institutes of Health (NIH) supported the development of 99 drugs from 1996-2020 — a total that includes 16 percent of all such treatments that made a “significant” advance over available medicines.

  • Read more about Report: NIH SBIR/STTR program supported 99 drugs, numerous successful companies over 25 years

Useful Stats: Measuring NIH SBIR/STTR Awards by State, 2019

Thursday, April 30, 2020

In this week’s edition of Useful Stats, we take a look at NIH’s SBIR/STTR program by state, including the success rate of applications, the share SBIR awards make up of NIH funding to for-profit companies by state, and the total number of awards by state. It should be noted that SSTI was able to prepare this information because of the excellent transparency of information that NIH offers on its website, a model that should be replicated by other federal agencies.

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Recent news from the SSTI Digest

Place-based innovation comes of age: Federal regional innovation programs are reshaping America's technology economy

Wednesday, August 5, 2026
Strong regional ecosystems connect universities, entrepreneurs, investors, manufacturers, workforce organizations, and state and local governments. Rather than supporting just isolated institutions, federal agencies are now investing in collaborative regional networks capable of translating research into new companies, industries, and jobs. The intent is not for every region to become the next Silicon Valley, but to enable regions to compete by organizing around what they already do well.
NSF
EDA
tech hubs
NSF Engines

Takeaways from the ACA angel capital report

Wednesday, August 5, 2026
As SSTI noted in its recent look at quarterly investment activity, gaining insight into angel investment is difficult because of the challenges of separating angel activity from seed and other early VC transactions. Fortunately, the Angel Capital Association (ACA) recently published a report that provides a deep dive into 2025 angel investment activity and provides more clarity on this important financial partner for regional innovation. The big picture takeaway from the ACA report is that, like VCs, angel groups are making larger investments in fewer companies. 
angel capital

State grant programs support manufacturers and improve their competitiveness

Wednesday, August 5, 2026
As those involved with the longstanding, internationally recognized program know, an air of uncertainty has enveloped NIST’s Manufacturing Extension Partnership (MEP) for the past two years. With the release of the new Notice of Funding Opportunity (NOFO) for MEP Centers (see SSTI’s write‑up here), it appears that perhaps many of those troubles may be in the past. Even so, the uncertainty has prompted many manufacturers, small businesses, and MEP centers to explore alternate funding sources, partnerships, and forms of assistance beyond NIST.
MEP
states
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