Nearly 1 in 6 adults carrying outstanding student loan debt (1 in 3 among 18 to 29 year olds), with both the number of borrowers and the debt amount increasing in recent decades. Meanwhile, the share of new entrepreneurs aged 20 to 34 declined from 34 percent to 27 between 1996 and 2019, and a new issue brief from the Ewing Marion Kauffman Foundation notes that among individuals who start businesses, higher levels of student loan debt are negatively related to business income and employment. Noting that the debt can directly affect an individual’s overall personal financial resources, and indirectly affect ability to start a business, the brief extends some considerations for decision makers who seek to respond to those challenges.