The National Nanotechnology Initiative (NNI), established in 2001 as a collaboration of 20 federal agencies and cabinet-level departments with an interest in nanotechnology R&D and commercialization, has released a draft of its 2016 strategic plan. The National Nanotechnology Initiative Strategic Plan, which describes the initiative’s vision and goals as well as potential strategies to achieve these goals. The plan is an update to and a replacement of a plan originally released in December 2013. Prior to the new plan’s official publication, the public is encouraged to submit comments online by September 23, 2016.