If a concentration of highly skilled workers is an important leading indicator to more widespread economic growth, which regions are leading the way? Using data from the Current Population Survey (CPS) to compare the educational attainment rates of the nation’s largest labor forces from 2005 to 2013, authors from the Cleveland State University Maxine Goodman Levin College of Urban Affairs determine where America’s highest-skilled jobs are clustering. In ranking the percentage of labor force with a graduate or professional degree in 2013, the list of top five regions is perhaps unsurprising: Washington, D.C., San Jose, Boston, San Francisco, and New York – considered first-tier metros by nearly all accounts. In assessing the percent point change between the percentage of workers with an advanced degree in 2005 and in 2013, however, “second-tier” metros begin to emerge as leaders.