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VC data highlights what types of deals are slowing early-stage investment activity

Long concentrated geographically, venture capital also is growing more concentrated in a small number of larger deals, as SSTI has reported in recent Digest issues. In fact, deals under $100 million—not a small figure in itself—have fallen by 71% according to SSTI’s analysis of PitchBook data. Even more troubling is evidence showing deals under $100 million are moving to later-stage investment and away from early-stage companies. The trend, SSTI believes, should be of concern for nonprofit venture development organizations as well as TBED policy makers and regional stakeholders working to keep their local economies competitive through innovation-driven entrepreneurship. This shift in private capital market behavior may have negative impacts on company survival rates, downstream economic growth opportunities, and the long-term competitiveness of U.S. industry.

Recent Research: Are SBIR-funded inventions more likely to make it to market?

Commercializing patented inventions is a common goal of innovation policy, as it drives company revenues and regional economic growth. However, tracking the commercialization of inventions stemming from R&D is challenging. While programs like the Small Business Innovation Research (SBIR) program are explicitly designed to encourage commercialization, most evaluation tools rely on approaches that may be anecdotal or incomplete, such as surveys, case studies, or patent counts. A working paper by Carlo Bottai, Gaétan de Rassenfosse, and Emilio Raiteri proposes a new web-based methodology for detecting commercialization, offering a potentially more objective, real-time way to gauge the return on public innovation investments. It might prove a useful tool for state TBED programs that support R&D grants, research centers, and university-industry research collaboration.

NIH and NSF respond to order for “gold standard science”

As agencies begin delivering their implementation plans in response to President Trump’s executive order that called for the implementation of “gold standard science (GSS)” and asserted that “(r)eproducibility, rigor, and unbiased peer review” must be maintained, the proposed agency actions appear less disruptive than many funded parties had feared. NIH notes that its embrace of GSS is a continuation of its existing commitment to scientific excellence and that the agency “welcomes the opportunity to reaffirm its continued commitment to this goal.” NSF sets forth plans to “redouble” its commitment to GSS. 

New report from AURP describes significant impacts of research parks

Research parks in North America impact innovation communities in key areas, including the economy, jobs, occupancy, culture and placemaking, cluster development, entrepreneurship, and development and growth. In its recently released 2025 Economic Impact Report, The Power of North American Research Parks, the Association of University Research Parks (AURP) presents data that shows just how significant these impacts are.

Useful Stats: Growth in real business R&D expenditures comes to a halt in 2023

From 2022 to 2023, domestic R&D expenditures increased 4%, or $29 billion, but remained nearly unchanged when adjusted for inflation. This apparent slowdown follows a streak averaging nearly 12% ($59 billion) year-over-year growth from 2018 to 2022, and 8% over the past decade from 2014 to 2023. Adjusting for inflation paints a different picture of the growth trends, with a more modest annual average of 8% from 2018 to 2022 and 6% over the past decade. In this edition of Useful Stats, SSTI uses new Business Enterprise R&D (BERD) survey data to explore business R&D expenditures since 2009. Then, we present the data by sector and industry, allowing for closer analysis of which business R&D see the most investment in the U.S.

Free college programs remain popular nationwide

“Buckeye Bridge,” a new initiative between The Ohio State University and Columbus State Community College, will provide students with a tuition-free path to finish their bachelor’s degree. Low- to middle-income Ohioans who earn an associate degree from Columbus State will qualify for the new program at Ohio State, which will cover all tuition and mandatory fees.

SSTI Board of Trustees appoints Nick Maynard to the board

The SSTI Board of Trustees has appointed Nick Maynard, co-founder and CEO of US Ignite, as a member of the board. “I'm excited to work with Nick as he joins SSTI's board,” said Mark Skinner, CEO of SSTI. “Since meeting Dr. Maynard fifteen years ago, he has proven in my estimation to be one of the brightest, most thoughtful, solutions-oriented people in the country working to advance regional economic growth through innovation."