SSTI Digest

AlphaLab Health, an accelerator program developed by Innovation Works (IW) and Allegheny Health Network (AHN) for life-sciences startups in the Pittsburgh region, has received a $10 million grant from an anonymous donor. The grant establishes the AlphaLab Health Revolving Investment Fund, which will support startups in the accelerator program. According to a press release from AlphaLab Health, the investment returns generated by the fund will create a “permanent, self-sustaining source of revenue that will be reinvested into future AlphaLab startups.” 

New House appropriations committee chair Tom Cole (R-OK) has announced a rule that nonprofits are not eligible for “community project funding” (i.e., earmarks) from the Department of Housing and Urban Development’s Economic Development Initiative in the FY 2025 appropriations bill. In FY 2024, this account provided $3.3 billion to public and nonprofit organizations, and CQ Roll Call reports that nearly $800 million of the House’s projects went to nonprofits. The rules for FY 2025 also maintain the ban Cole’s predecessor, Rep. Kay Granger (R-TX), placed on all earmarks in the Labor-Health and Human Services-Education funding bill. At this point, the Senate does not seem likely to conform with the House’s change—the Senate has not published a change to its guidance and did not follow the House’s restrictions in FY 2024.

While the growth of female-founded and co-founded companies has increased at a faster rate than those of male-founded and co-founded and mixed gender founded companies, it is still a smaller amount than the other two. Additionally, these companies are more likely to receive a higher proportion of deals occurring earlier in the VC pipeline.

In the 21st century, some high-tech firms in emerging fields are valued more for their perceived innovation potential than by traditional measures of a successful business. But how does innovation influence the value of existing publicly traded firms? New research by Panteleimon Kruglov and Charles Shaw explores the relationship between R&D intensity and financial performance among S&P 500 companies over 100 quarters from 1998 to 2023 and its implications for firm competitiveness and market positioning.

The measurements for success of female-founded and female-co-founded companies, while improving, remain lower than male-founded companies in number, deal count, and capital invested, according to PitchBook’s 2023 Annual US VC Valuations Report. PitchBook found that female-only-founded startups received just 2% of all venture capital (VC) dollars in 2023, while those female-co-founded reached 21% that year—a record high. SSTI analysis of PitchBook data finds that the number of VC deals to female-founded and female-cofounded companies has increased 58% over the past decade, yet despite reaching that milestone, they have been on a sharp downward trend since 2021.

“Inclusive clusters have an explicit focus on equity, have identified the precise issues that lead to economic disparities in the cluster and have targeted strategies in place to shrink those disparities,” say the authors of Developing Inclusive Clusters, a recent Insight Report from the New Growth Innovation Network (NGIN) and RTI International. They cite the high-tech industry as a high-wage industry whose benefits “tend to exclude women, people of color, and non-urban communities” and note that this type of disparity has not been “widely or systematically” studied.

On Wednesday, the STEMM (Science, Technology, Engineering, Mathematics, & Medicine) Opportunity Alliance announced STEMM Equity and Excellence 2050: A National Strategy for Progress and Prosperity. In a press release, SOA also announced that its partners have collectively committed more than $2 billion to realize the vision of the national strategy, each committing to “multi-lateral, cross-sector collaboration to achieve systems-level change.”

The Internal Revenue Service (IRS) has released its final rules, as required by the Inflation Reduction Act, to make many clean energy tax credits transferable (able to be sold to a third party) or available for elective pay (a direct payment to the credit holder). Both rules may help expand investment in clean energy by providing mechanisms that get capital to the project’s developer immediately, even if the developer is a nonprofit or public entity that would never have paid any taxes on the project. Credits covered by the rules include the production tax credit, investment tax credit, advanced manufacturing credit, and the hydrogen production credit. For more information on the energy tax credits renewed or created in the Inflation Reduction Act, visit epa.gov; for the new IRS rules, visit treasury.gov.

May 21, 2024, 3:00 p.m. ET

Traditionally, a scientific discovery's commercial potential is gauged after significant R&D. However, a recent paper by Duke University researchers Roger Masclans-Armengol, Sharique Hasan, and Wesley M. Cohen (2024) proposes a new method for assessing the commercial potential of scientific research before it's fully developed. Using a large language model to analyze scientific findings, the researchers predicted the likelihood that a discovery will lead to marketable products or processes.

Rev1 Ventures, an investor startup studio in Columbus, Ohio, that combines capital and strategic services to help startups scale and corporations innovate, recently released its 2023 Startup Impact Report. The report notes the entrepreneurs they supported last year raised $390 million in capital with 34 raising pre-seed capital, 16 seed capital, and 19 early-stage capital. The clients generated $192 million in revenue and created or retained 1,013 jobs.  Rev1 invested $6.4 million in 17 companies in 2023 and supported a variety of startups, “including enterprise SaaS technology creating efficiencies in insurance and real estate, advanced technologies in green energy and life science disruptors with novel therapeutics for genetic diseases with no current cure.” Additionally, Rev1 reports the companies it has supported over the last 10 years have surpassed $5 billion in total economic impact in Ohio.

The U.S. Small Business Administration (SBA) has announced the 2024 Growth Accelerator Fund Competition (GAFC) Stage One winners. Each received $50,000 in prize awards for impactful and inclusive approaches to foster a thriving, collaborative national innovation support ecosystem to advance small business R&D. The SBA press release announcing the winners stated that “GAFC Stage One winners are organizations with ecosystem-building activities, including recruitment of new partners and strengthening existing alliances among stakeholders (including public, private, nonprofit, and academic partners), that aligned their submission with one of the following GAFC Theme Areas” of national and economic security; domestic manufacturing and production; and, sustainability and biotechnology.