National Institute of Health (NIH) Director Francis S. Collins has accepted recommendations from an NIH working group that call for increased investment in the federal government’s effort to map and understand the human brain. Under the recommended plan, the initiative would receive $400 million each year between 2016-20, which would grow to $500 million a year for 2021-25. The BRAIN Initiative is a multi-agency effort, supported by NIH, Defense Advanced Research Projects Agency of the U.S. Department of Defense, National Science Foundation and Food and Drug Administration.