SSTI Digest

With Q1 2025 venture capital (VC) data stabilized and reports coming out on investment activity, it is a good time to review 2025 VC investment from a TBED perspective. Many published reports on VC activity include deals at the top end of the size range that—with individual transactions now reaching- billions of dollars—can swing some of the metrics and mask the underlying nuances facing smaller companies and markets. While investment levels are trending up, the totals are driven by mega deals and AI companies. Looking deeper into the numbers, there appears to be a broad shift away from smaller investments toward larger deals. This shift raises important questions for publicly supported innovation finance programs intended to close financing gaps and provide technical assistance that prepares companies for larger investments. 

The U.S. Small Business Administration posted a notice in the June 9, 2025, Federal Register of SBA’s intent to establish a Manufacturing in America Advisory Committee to “provide strategic guidance, advice, and recommendations to the U.S. government and relevant stakeholders on matters related to growth, supply chain resilience, and innovation of small manufacturing businesses across the country. The committee will act as the collaborative body to ensure the sector's needs, challenges, and opportunities are addressed. The committee's mission over the next two years will focus on supporting economic growth, job creation, on-shoring of critical manufacturing capabilities, and global competitiveness.”

Adrienne Johnson, committee management officer in the Office of the Administrator, is listed as the SBA contact for those seeking more information. (202) 205-6685 or FACA@sba.gov.

The U.S. Department of Commerce recently announced that the agency formerly known as the U.S. AI Safety Institute has been renamed the Center for AI Standards and Innovation (CAISI). The center’s priority focus areas also have been adjusted so that CAISI can serve as industry’s primary point of contact within the U.S. Government to facilitate testing and collaborative research. According to the Commerce announcement, CAISI will:

In 1978, Massachusetts took a risk and made an $8.5 million investment into one of the earliest technology-based economic development (TBED) initiatives in the world. The commonwealth, among the states hard-hit by the global manufacturing restructuring underway at the time, which led to the deep recession of the early 80s, knew it needed to try something different to restore its economy and its long-term competitiveness. A new independent impact analysis of the cumulative impact from what became known as MassVentures, spanning its 46-year history, should serve as an example of what public seeding and sustained support for TBED can deliver as a highly effective, game-changing economic development strategy. 

MassVentures President and CEO Charlie Hipwood said at the report’s release, “MassVentures is one of the most successful and impactful government-initiated programs on a per dollar basis in the United States.” The annualized impact figures and VC-envying returns bear out the proud statement.

Tuesday, July 1 | 3:00 p.m. EST

Whether your region is just beginning to address market failures in risk capital availability and performance for innovation-centered companies or your current efforts could use a refreshing check-in among peers, please plan to join us for the kick-off of our Innovation Finance Community of Practice Series. 

On June 3, SSTI will host a webinar exclusively for Innovation Advocacy Council members to receive an in-depth update on many of the confusing factors in play in the federal policy and budget environments—the key factors influencing the future of your state, regional and university TBED strategies. IAC partners at Van Scoyoc & Associates will be on hand to provide the latest news from the Hill and answer questions to help make sense of any new developments.

From reconciliation to rescissions to possible impoundment to skinny and full budgets, the FY2025 and FY2026 budget process is one for future history books and too complicated for TBED leaders to stay fully abreast of while meeting your mission objectives. That’s where the IAC comes in! Keeping track of these developments and helping us map our best funding strategies for the best service delivery is why IAC has partnered with the amazing VSA team. 

The list of technology-based economic development initiatives within the newly created Technology and Innovation Office of the New Mexico Economic Development Department covers the spectrum of critical policy aspects required for a strong state innovation economy: increasing R&D, business incubation, targeted emerging technologies and strong existing assets, startup capital, venture development, and innovation talent development and recruitment. With Governor Michelle Lujan’s signing of House Bill 20, which commits nearly $93M of public dollars—much or most requiring private match—the new office represents a serious investment from a state of just over 2.1 million people.

The new Technology and Innovation Office will absorb the former Office of Strategy, Science and Technology and will include the following priorities: 

Note: TBED101 is a new, occasional series for Digest readers visiting and revisiting fundamental topics for nurturing strong regional innovation economies. SSTI is introducing this series, with EDA support, as the field has entered one of its most significant periods of disruption and change in its 45-year history. Separately, SSTI members will be able to participate in more in-depth explorations of the issues in the coming months as part of their membership. Consider joining here.

If you’re leading a knowledge work[1] organization and considering introducing generative artificial intelligence into your workflow, it likely would be helpful to know how its use may impact the day-to-day aspects of your team’s work, and the potential risks involved. 

A recent study by researchers at the University of Chicago and Argonne National Laboratory provides a resource for understanding organizational adaptation of generative AI. They surveyed science and operations employees in the lab to learn about their perceptions and concerns of the potentially transformative or possibly disruptive technology. With responses divided between science and operations workers, the researchers then conducted follow-up interviews with one-third of the group.

For the United States to achieve greater security in chip manufacturing, the critical sector requires a much larger, better trained workforce. Between 2020 and 2022, annual postings for semiconductor jobs tripled from about 8,000 to almost 25,000, according to a new report, “The challenge of building a regional semiconductor workforce pipeline: What regions can learn from Austin, Texas and an agenda for cross-regional learning” from the Institute for Networked Communities (INC). As noted in the report, analysts expect that between 2023 and 2030, the industry will grow 33%, an increase of 115,000 jobs.

The White House Fiscal Year 2026 discretionary budget proposal outlines a significant shift in federal spending priorities, proposing substantial reductions in innovation and non-defense discretionary funding, which, if enacted by Congress, would impact scientific research and regional economic development support across numerous federal agencies. 

The initial release of the White House's FY2026 budget proposal is characterized as a "skinny budget," indicating that it provides a high-level overview of the administration's discretionary spending priorities without the detailed line-item specifics contained in a full budget request. The proposal aims for a $163 billion cut in non-defense discretionary funding, a 22.6% reduction from the previous fiscal year. 

The United States faces intense competition in global markets for advanced technology industries. The Information Technology and Innovation Foundation (ITIF) article, "The State Hamilton Index: Most states underperform in advanced industries" by Meghan Ostertag reveals a concerning trend regarding the geographic distribution and overall strength of advanced industries within the U.S. The 2025 State Hamilton Index indicates that most U.S. states lag behind both the global average and China in their concentration of employment in advanced industries deemed crucial for economic growth and national security. Only four states don’t lag across multiple sectors, and only one beats China.