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April 16, 2025, 2:00pm EDT
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How one applies and has their proposal reviewed to gain a small share of the world's largest funding source for life science research is changing. The following highlights modifications affecting grant applications submitted to the National Institutes of Health for due dates on or after January 25, 2025, as posted on their Implementation of New Initiatives and Policies page.

Many metropolitan areas grapple with demographic shifts, labor shortages, and changing economic conditions, so understanding the factors that encourage former residents to return may help policymakers design more effective strategies for talent retention and regional revitalization.

White House

The Senate has confirmed Michael Kratsios to serve as director of the Office of Science and Technology Policy. 

Pennsylvania Gov.

As U.S. research institutions face funding uncertainty, countries and universities worldwide are launching initiatives to lure away our scientific talent:

NOTE: The nation's community of technology-based economic development organizations is in its annual report season, and we've already seen several releases from SSTI members. All document TBED's impact on advancing research, moving it to market, and helping businesses improve their profitability and competitiveness.

In a country marked by regional diversity, gaining insights into economic performance often means looking beyond conventional state and county boundaries to economic hubs. This edition of Useful Stats uses Bureau of Economic Analysis (BEA) data to first compare U.S. metropolitan and micropolitan GDPs broken down by industry for the last 20+ years, then consider each Metropolitan Statistical Area’s GDP by private industry, highlighting patterns and changes over the past decades.  

California Gov.

Regional cooperation economic development is believed to stimulate growth in various ways, including increased trade, enhanced movement of technologies from lab to market, and improved resource allocation. Federal support for innovation-driven growth has increasingly forced applicants to take integrated regional approaches. However, empirical evidence on the specific impacts of such cooperation is scant.

A recent Executive Order from the White House could jeopardize the Community Development Financial Institution (CDFI) Fund and put at risk investments in small businesses. The EO calls for the “non-statutory components and functions” of several governmental entities, among them are the CDFI and the Minority Business Development Agency, “to be eliminated ...

In this final coverage of gubernatorial addresses as they discuss the innovation economy, the following highlights have been selected from State of the States or budget addresses given between Feb.

The Small Business Innovation Research (SBIR) program is one of the federal government's most substantial investments for moving innovation from America’s small businesses into the private market or federal procurement in areas like defense, space, energy or transportation.

The Angel Capital Association (ACA) reports seed stage investments accounted for almost 60% of the total angel deals in 2021, up from 50% in 2020.  These seed stage angel investments represented more than half of the $950 million invested by 180 ACA member groups in 2021.  ACA estimates that portfolio companies raised more than $5 billion, suggesting leverage of more than 5X their initial angel investments. Based on member-submitted direct investment data, the 2022 Angel Funders Report provides an overview of early stage investment trends.

NOTE: The nation's community of technology-based economic development organizations has entered the annual report season, and we've already seen several releases from SSTI members. All document TBED's impact on advancing research, moving it to market, and helping businesses improve their profitability and competitiveness.

A recent working paper from the Federal Reserve Bank of Boston, Self-reinforcing Glass Ceilings by Carlos F. Avenancio-León, Alessio Piccolo, and Leslie Sheng Shen delves into the complexities of the gender pay gap, even after it has narrowed. The authors challenge the conventional understanding that a shrinking gender pay gap automatically leads to greater gender equality.

Wednesday, March 19, 3:00 pm EDT | Zoom
No charge; registration required.

A two-page proposal for a $40,000 Phase IA award? Phase II performance ratios required for companies receiving 10 and 25 Phase I awards over their lifetime? Halving the budget for STTR and shrinking university partner share? Creating a 0.25% carve-out of DOD SBIR funds for phase III awards up to $30M each? Limiting all federal technical assistance and outreach to 25 states with the fewest SBIR/STTR awards? Stronger, broader, tougher foreign risk requirements for the companies and agency due diligence? 

By automating routine tasks, improving data analysis, and enhancing marketing efforts, AI can revolutionize how small firms conduct business—and that should impact the type of assistance technology-based economic developers offer their innovation-driven entrepreneurs. Understanding how small business owners perceive and utilize AI is crucial for developing strategies that support their growth and competitiveness. 

Overall U.S. gross domestic product (GDP) has steadily increased over the past decade. However, the growth in the sectors which drive it has been uneven. Data from 2014 through 2023 reveals that sectoral contributions to private industry GDP have shifted from manufacturing (down 1.57 percentage points since 2014) and mining, quarrying, and oil and gas extraction (down 1.05), to professional and business services (up 0.85) and construction (up 0.72).

NOTE: The nation's community of technology-based economic development organizations has entered annual report season, and we've already seen several releases from SSTI members. All document the impact TBED can have on advancing research, moving it to market, and helping businesses improve their profitability and competitiveness.

NOTE: The nation’s community of technology-based economic development organizations has entered annual report season, and already we've seen several released from SSTI members. All document the impact TBED can have for advancing research, moving it to market, and helping businesses improve their profitability and competitiveness.

As this week’s recent research article mentions, R&D tax credits work, so it isn’t surprising several states have either proposed, amended, or enacted research and development (R&D) tax credits for both the current fiscal (2025) and new (2026) fiscal year in efforts to encourage innovation and economic growth. Some specifically target life sciences or biotechnology sectors while others focus on attracting new or existing companies and startups or to further develop life sciences and/or biotech sectors and hubs.