TBED Works: Sandia spinout creates commercial opportunities for lab-developed technologies
The state of US venture capital investment in four charts. How might your innovation startups fare if investment trends hold?
With 2025 behind us, and some time for the data to stabilize, we can look back at VC activity and try to understand what it means for TBED efforts going forward. The VC storyline of 2025 should be familiar to anyone who has been following investment news. Record funding rounds, huge amounts of capital deployed, questions of an AI bubble. Where amongst the big flashy lights of AI mega-deals do we find the subtlety and nuance that informs TBED investor activity and policy?
With 2025 behind us, and some time for the data to stabilize, we can look back at VC activity and try to understand what it means for TBED efforts going forward. The VC storyline of 2025 should be familiar to anyone who has been following investment news. Record funding rounds, huge amounts of capital deployed, questions of an AI bubble. Where amongst the big flashy lights of AI mega-deals do we find the subtlety and nuance that informs TBED investor activity and policy? Looking closely at historical trends and segmenting the data by deal size highlights what most companies seeking funding face and points to potential outcomes for 2026.
Recent Research: Adapting tech transfer for the 21st Century
In the last twenty years, there has been a critical shift in the technology transfer landscape that calls for a fundamental overhaul of university Technology Transfer Offices (TTOs) from focusing on passive IP management to active startup development, according to a recent SSRN article.
AlphaLab Health, Innovation Works and Allegheny Health Network joint venture, receives $10 million grant
AlphaLab Health, an accelerator program developed by Innovation Works (IW) and Allegheny Health Network (AHN) for life-sciences startups in the Pittsburgh region, has received a $10 million grant from an anonymous donor. The grant establishes the AlphaLab Health Revolving Investment Fund, which will support startups in the accelerator program.
Georgia Research Alliance companies raise more than $2B in venture capital
The Georgia Research Alliance (GRA) — a nonprofit working to grow Georgia’s economy through supporting research at state universities — recently announced that its portfolio of companies had raised more than over $2 billion in venture capital. These startups also had a high survival rate — 88% were still in business four years after launch, outpacing the national average of 44%. Along with this announcement, GRA released 2021 data on their economic impact on the state, demonstrating growth from the previous year.
Decoding Scaleup Success: Networks, ESOPs, and Advisors Make the Difference
Startup Genome and the Global Entrepreneurship Network recently released a new report offering a fresh perspective on what it takes for a startup to scale. The report draws on an eleven-year study involving 100,000 startups to provide a nuanced look at the factors contributing to startup scalability, offering actionable insights that underscore the importance of networks for entrepreneur support organizations, entrepreneurs, and policymakers.
DHS issues proposed rule to modernize the H-1B visa program, includes startup founder provision
A proposed Department of Homeland Security (DHS) rule could herald significant changes to the H-1B specialty occupation worker program.
$6 million in funding made available to Michigan startups
Last week, $6 million in funding was approved by the Michigan Strategic Fund for startup companies in the state. The $3 million Pre-Seed Fund III granted by the Michigan Economic Development Corporation will be administered by the Michigan State University Foundation and will support early-stage startups.
Recent Research: The key role of immigrants in the U.S. innovation ecosystem
As the U.S. seeks to maintain its competitive edge in the global economy, it is important to acknowledge the contributions of immigrant innovators toward U.S. growth and competitiveness. Despite making up only 16% of the population, immigrant inventors are responsible for approximately 36% of the U.S. innovative output since 1990, and have founded some of the most successful companies in the nation.
Advanced technology entrepreneurs meet America’s Seed Fund reps at four-day online event
America’s Seed Fund Week, a Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) event, will be held online May 15-18. The event connects entrepreneurs and organizations that support entrepreneurs to SBIR and STTR, known as America’s Seed Fund. America’s Seed Fund is the largest source of early stage funding in the U.S.
The State of Startups: A review of recent research
In a recent economic brief, Why Are Startups Important for the Economy?, the Federal Reserve Bank of Richmond provides a comprehensive review of the current literature around startups, their impact on productivity and job creation rates, and their significance in the U.S. economy.
In a recent economic brief, Why Are Startups Important for the Economy?, the Federal Reserve Bank of Richmond provides a comprehensive review of the current literature around startups, their impact on productivity and job creation rates, and their significance in the U.S. economy.
Gender and racial makeup of startup's founding team impacts funding
A recent report by DocSend Inc., a subsidiary of DropBox, surveyed over 300 pre-seed startups, finding that on average, in terms of gender alone, mixed teams raise the most funds, while all-male teams raise the least. In terms of both gender and race, on average, mixed gendered teams with minority members raise the most funds while all-male teams with no minority members raise the least.
Energy storage startup with government-sponsored funding goes public
ESS Inc., a company that closed a deal to go public earlier this month, was able to leverage public capital at its early stages to accelerate its success as a startup. Founded in 2011, the Wilsonville, Oregon, based company manufactures batteries for long-duration energy storage applications. In 2012, ESS Inc.
ESS Inc., a company that closed a deal to go public earlier this month, was able to leverage public capital at its early stages to accelerate its success as a startup. Founded in 2011, the Wilsonville, Oregon, based company manufactures batteries for long-duration energy storage applications. In 2012, ESS Inc. received a Phase I Small Business Innovation Research (SBIR) award from ARPA-E, and additional grant support from the Oregon Nanoscience and Microtechnologies Institute (ONAMI), an SSTI member. ONAMI is an Oregon-based non-profit that provides grants, equity funding and business development guidance to startups engaged in research-based scientific innovation. It receives funding from Business Oregon, also an SSTI member.
How new antitrust rules may affect tech startups
In Washington and Brussels, lawmakers are increasingly vocal about expanding the application of antitrust rules within the tech sector.
In Washington and Brussels, lawmakers are increasingly vocal about expanding the application of antitrust rules within the tech sector. Recent activity includes a report from Democrats on the House antitrust subcommittee, the Trump administration preparing an antitrust suit against Google, and the European Union (EU) considering new antitrust rules following billions of dollars in fines to major tech companies. While much of these actions’ coverage focuses on how changes would affect the companies that are being targeted by these efforts, the impacts would affect the entire tech sector.
UK, France, Germany commit $8.1 billion for startups
Earlier this week, the United Kingdom announced a £1.25 billion ($1.6 billion) initiative to support the country’s startups. One program within the initiative provides £500 million in the form of loans up to £5 million that are matched by private funders to companies that have raised at least £250,000 in the last five years. The remaining £750 million will be managed by Innovate UK and provide loans and grants to R&D-focused companies. The U.K.
SBA PPP loans approved in all states, Great Plains lead per capita distribution
SBA released data on the Paycheck Protection Program (PPP) this week for all approved loan activity through April 13 and told banks Wednesday night that the program is nearly out of funds. The data show more than 1 million loans worth more than $247 million approved across all states and territories.
Startup trends examined in recent reports
While startups consistently create more jobs than older firms, the Federal Reserve Bank of St. Louis took a look at the trends in startup’s share of jobs and found that startup employment share has been declining for more than a decade. The Fed story provides an overview of startup employment dynamics between 1994 and 2018.
Accelerators help improve efficiency of startup capital
Over the last decade, accelerators have spread from a Silicon Valley phenomenon to communities across the country. Questions, however, remain on their impact on startups and whether they aid in creating a strong startup ecosystem. In How Do Accelerators Impact High-Technology Ventures?, Sandy Yu from UC-Berkeley found that the accelerator process helps resolve uncertainty around company quality sooner than what is experienced by non-accelerator companies.
Venture-backed Relativity Space poised to disrupt US commercial spaceflight
Founded in 2015, venture-backed aerospace firm, Relativity Space, is poised to disrupt the rocket manufacturing and launch markets as it secures long-term contracts at NASA’s Stennis and Kennedy Space Centers. Relativity is reimagining the process to iterate and scale rockets quickly, relying on its revolutionary “Stargate” metal 3D printer and new autonomous facilities to build and launch rockets in days rather than years.
Report identifies novel approaches to supporting energy hardware innovation
Emerging over the past five years, novel approaches to supporting early-stage cleantech development have the potential to ease the transition from invention to marketplace, according to new research from the National Renewable Energy Laboratory’s (NREL) Innovation & Entrepreneurship Center for the Joint Institute for Strategic Energy Analysis. The report provides a comparison of some of the nation’s most notable cleantech incubators and accelerators, finding that each organization fills a unique niche and competition among them is not an issue.
Female-led startups and investors face uphill battle in VC industry
Both female-founded startups and female investors have seen slow progress over the past 10 years, and still face an uphill battle for equality in the venture capital industry. While the deal count for companies founded solely by women has more than quadrupled since 2008, the share of venture dollar invested has remained nearly flat, hovering around 2.0 percent over the same time, according to PitchBook.
Startups, investors may bear brunt of escalating US-China tensions
Last week, U.S. trade representatives traveled to Beijing for a round of trade talks with the hope of coming to an agreement that would end the U.S.-Chinese trade dispute. Alongside large corporations, many U.S. tech startups are watching the results of these talks with a close eye because they face significant concerns over the impact that increased tariffs will have on their business. But while tariffs have garnered most of the press attention, U.S.
Last week, U.S. trade representatives traveled to Beijing for a round of trade talks with the hope of coming to an agreement that would end the U.S.-Chinese trade dispute. Alongside large corporations, many U.S. tech startups are watching the results of these talks with a close eye because they face significant concerns over the impact that increased tariffs will have on their business. But while tariffs have garnered most of the press attention, U.S. startups also face reduced access to foreign capital, increased regulatory scrutiny, and potential talent issues. Conversely, China is developing new strategies to ensure that more investment dollars will remain in their domestic startup capital community.
Women hold only 9 percent of equity value in their startups, report finds
While women comprise approximately 33 percent of the combined founder and employee workforce at startup companies, they hold just 9 percent of all equity value in those companies, according to The Gap Table from Carta – a software platform for managing startup equity and ownership. The new report was based upon capitalization table (cap table) data from more than 6,000 companies with a combined total of nearly $45 billion in equity value.
While women comprise approximately 33 percent of the combined founder and employee workforce at startup companies, they hold just 9 percent of all equity value in those companies, according to The Gap Table from Carta – a software platform for managing startup equity and ownership. The new report was based upon capitalization table (cap table) data from more than 6,000 companies with a combined total of nearly $45 billion in equity value. The cap table is a list of owners of a company and includes information about the percentages of ownership, equity dilution, and value of equity in each round of investment. The researchers found that:
- Women make up 35 percent of equity-holding employees, but only hold 20 percent of employee equity; and,
- Women make up 13 percent of founders, but hold 6 percent of founder equity.
Factors influencing successful angel investing subject of new initiative
The Angel Capital Association is piloting a new report on the factors that influence successful angel investing and the startups that angels support. The initial Angel Funders Report covers 2017 data from 26 angel groups and provides new insights for one year of investments. Some of the report’s key findings include:
University conferences aim to win with entrepreneurship
A new platform to match promising start-ups with experienced business executives, investors and startup mentors from participating school’s alumni ranks is reporting momentum.
A new platform to match promising start-ups with experienced business executives, investors and startup mentors from participating school’s alumni ranks is reporting momentum. Following a year of development, the University of Kentucky last month announced the launch of the Southeast Executives-on-Roster (XOR) and the Midwest Executives-on-Roster (XOR) platforms, collaborations between regionally-partnered universities to broaden access to experienced entrepreneurial talent and match that talent to university-affiliated startups in need of executive management. SSTI learned more about the program through interviews with two of the universities involved.