TBED Works: How to transform from “flyover” to biotech cluster
FY 26 Commerce-Justice-Science appropriations passes House
Recent Research: How can states ensure effectiveness of R&D incentives?
State R&D incentive programs such as tax credits are widely used to stimulate innovation, attract investment, and support long-term economic growth. But how do we know which programs truly increase R&D activity rather than simply subsidizing what companies would have done anyway?
A year of uncertainty: 2026 brings fiscally challenged budgets and 36 gubernatorial elections
The new year begins with a layer of both fiscal and political uncertainty. For at least 18 states, it will be a year of change in political leadership. After several years of continuous revenue growth, states are crafting their Fiscal Year (FY) 2027 budgets amid slower growth, rising costs, and heightened unease.
TBED Works: MTI delivers on economic growth by supporting early-stage companies in targeted sectors
The Maine Technology Institute’s core mission is to use innovation to spur the development of new products, processes, and companies that strengthen the state’s economy. Finishing its 25th year of operations, MTI solidly illustrates how a sustained, focused yet flexible and creative strategy can deliver this mission. MTI has disbursed $387 million across 4,350 distinct projects throughout Maine since its founding, and that funding has leveraged over $2.2 billion in private sector matching investment.
Useful Stats: Higher education R&D expenditures reach $117 billion in FY 2024
Higher Education R&D expenditures jumped 8%, or nearly $9 billion, from fiscal year (FY) 2023 to 2024, reaching an all-time high of over $117 billion, reveals new Higher Education R&D (HERD) survey data. The funding sources of HERD expenditures remain proportionally unchanged from the prior year, with all sources increasing, and the federal government ($5 billion) and institution funds ($2.5 billion) accounting for the largest dollar increases.
Higher Education R&D expenditures jumped 8%, or nearly $9 billion, from fiscal year (FY) 2023 to 2024, reaching an all-time high of over $117 billion, reveals new Higher Education R&D (HERD) survey data. The funding sources of HERD expenditures remain proportionally unchanged from the prior year, with all sources increasing, and the federal government ($5 billion) and institution funds ($2.5 billion) accounting for the largest dollar increases.
Adjusted for inflation, overall HERD expenditures increased by 5%—the second largest year-over-year increase in the past decade—while all sources of funds except business increased.
Proposed biomanufacturing center may create competition among states
Times Higher Education finds interdisciplinary research drives university innovation
Serious birdwatchers know one finds the most variety in species where habitats collide, on the edges of domains. This also holds true for innovation, discovery, and scientific disciplines. Recent research shows that institutions that support interdisciplinary teams with strategic investments, institutional alignment, and collaborative ecosystems are more likely to create innovations that lead to patents, products, and companies.
Useful Stats: A standardized look at state-level academic S&E article output
States invest heavily in academic research with the expectation that these efforts will advance scientific knowledge, support innovative industries, and strengthen local talent pipelines. Comparing research performance across state lines is difficult due to differences in academic landscapes: some may have large medical schools with high-cost labs, while others have research-active public universities in lower-cost fields or are more pedagogically focused.
VC data highlights what types of deals are slowing early-stage investment activity
Long concentrated geographically, venture capital also is growing more concentrated in a small number of larger deals, as SSTI has reported in recent Digest issues. In fact, deals under $100 million—not a small figure in itself—have fallen by 71% according to SSTI’s analysis of PitchBook data. Even more troubling is evidence showing deals under $100 million are moving to later-stage investment and away from early-stage companies.
China's next goal: Global leadership in innovation
Recent federal plans are gearing up for bigger innovation role for AI-based research
A recent executive order from the White House establishes a “Genesis Mission” that aims to “mobilize the Department of Energy’s 17 National Laboratories, industry, and academia to build an integrated discovery platform,” according to a press release from the U.S. Department of Energy. The announcement builds on President Trump’s executive order, Removing Barriers to American Leadership In Artificial Intelligence, and his America’s AI Action Plan, released earlier this year.
Canada’s new budget prioritizes researcher recruitment and innovation amid geopolitical uncertainty
Canada's Prime Minister Mark Carney released his first federal budget on Nov. 4. The budget signaled the nation's commitment to research and innovation, while also revealing its readiness to meet the challenges of U.S. trade policies to Canada’s potential benefit. Research and innovation play key roles in its plans.
TBED Works: With significant early support from MassVentures, Cyvl applies technology innovation to public works
When Daniel Pelaez took a job with the Town of Southbury, Connecticut Public Works Department after his first year at Worcester Polytechnic Institute, he learned lessons that, a few years later, would become the basis for his startup, Cyvl. Daniel spent a season on the public works road crew fixing issues flagged by residents or found by the road foreman.
State News for December 11, 2025
Legislative & Federal News for December 11, 2025
Trump Administration seeks public input for advancing R&D, manufacturing
TBED Works: TBED organization supports the creation of entrepreneurship ecosystems throughout Indiana
Technology-based economic development organizations work with economic development professionals throughout the U.S. to help build their local innovation and entrepreneurship ecosystems. Sometimes, bringing in outside expertise with established networks to R&D and finance can accelerate the local capacity to support innovation-driven startups. gener8tor, a venture capital and startup accelerator founded in Wisconsin, is one such example of external partners supporting TBED capacity building anywhere.
What the proposed redefinition of “professional degrees” might mean for institutions, sectors, and workforce pipelines
The federal student loan landscape is undergoing its most sweeping restructuring in decades. Under the One Big Beautiful Bill Act (OBBBA) of 2025 and the U.S. Department of Education’s (ED's) proposed regulations, the definition of “professional degree” is being reinterpreted, sharply reducing the number of students eligible for the higher federal loan caps reserved for professional training.
Recent Research: Do mergers and acquisitions spur more or less innovation?
With fewer than 1,000 Initial Public Offerings in any year, the most common exit strategy for investors in early-stage innovation firms is to find an acquisition opportunity. For the broader economic goal of encouraging innovation because it drives growth and societal progress, when large firms acquire smaller, innovative companies, does it promote innovation, or does it primarily help dominant players thwart possible competition and consolidate market power?
Military’s critical technologies reduced to six priority areas
On Nov. 17, Under Secretary of War for Research and Engineering Emil Michael announced a trimmed-down list of six Critical Technology Areas (CTAs) as priorities for R&D and demonstration. Eight areas were dropped or incorporated within the new list.
When disaster strikes, TBED initiatives are focusing on economic and social impacts
Disaster relief is not directly within the purview of technology-based economic development organizations. Nonetheless, disasters frequently impact the partners and constituents of TBED organizations and exacerbate the social determinants of economic growth. Therefore, teams of people from TBED organizations frequently choose to step up and step out of their economic development sphere and engage in societal recovery from disasters.
Which states stand to benefit the most from the new Opportunity Zone criteria?
Just 19% of the approximately 25,000 census tracts potentially eligible for Opportunity Zone (OZ) designation are “More likely to attract OZ investment, with larger impact,” per the Urban Institute’s new OZ Designation Tool.1 The majority (68%) of potentially eligible tracts were found to be “Less likely to attract OZ investment,” while the remaining 13% were determined likely to attract capital regardless of OZ designation.
Statewide strategies are preparing for the new federal policy and funding landscape
ITIF warns that deep R&D cuts could have long-term economic impacts
Roundup of 2025 off-year elections
This week’s 2025 off-year elections resulted in two new governors, solidified legislative Democratic majorities in New Jersey and Virginia, and the approval of significant ballot measures in California and Texas. While the gubernatorial campaigns centered on affordability and tapped into an electorate’s concerns about state and national economies, they also kick off speculation on the 2026 midterms.