Most countries have dramatically increased their investments in R&D over the past two decades, with OECD nation spending reaching a record high nearly $1,600 of gross domestic expenditure on R&D (GERD) per person in 2023 (PPP[1] converted), approximately triple the value recorded in 2000. Although the U.S.

May 20, 2025, at 2:00 p.m. ET | Zoom 

SSTI’s recent webinar for its EDA-funded TBED Community of Practice work explored the emerging trend of creating centralized tech transfer offices (TTOs) serving multiple institutions. Centralized approaches are intended to more efficiently help develop and commercialize inventions from smaller or regional colleges and universities.

The AI market is projected to reach $4.8 trillion by 2023—a 25x increase in just 10 years, according to the UN Trade and Development (UNCTAD) 2025 Technology and Innovation report. The technology will be leap-frogging other “frontier tech markets,” including the Internet of Things, which currently dominates 36% of the market for emerging platform technologies. The super-charged AI market will impact up to 40% of global jobs, both positively and negatively.

For the United States to achieve greater security in chip manufacturing, the critical sector requires a much larger, better trained workforce.

Many SSTI members will attend the annual BIO International Convention, which will be held this year in Boston from June 16 to 19. There, they join a cohort of organizations with various connections to the life sciences, including contract research and manufacturing companies, academic centers, "big" pharma, "little" pharma, and foreign nations representing their life sciences efforts. 

With Q1 2025 venture capital (VC) data stabilized and reports coming out on investment activity, it is a good time to review 2025 VC investment from a TBED perspective. Many published reports on VC activity include deals at the top end of the size range that—with individual transactions now reaching- billions of dollars—can swing some of the metrics and mask the underlying nuances facing smaller companies and markets. While investment levels are trending up, the totals are driven by mega deals and AI companies.

In fiscal year (FY) 2023, federal obligations for science and engineering (S&E) to universities and colleges totaled $49 billion—$29 billion more than FY 2000, and a 10% increase from the prior year. The growth is less rapid when adjusted for inflation (2017 USD), with just over $40 billion in real obligations in FY 2023, a 5% increase over the year prior and $12.6 billion (or 46%) increase over the FY 2000 value.

The Australian Strategic Policy Institute’s (ASPI) report, ASPI’s two-decade Critical
Technology Tracker: The rewards of long-term research investment, aims to identify
which countries and institutions are leading in high-impact research across 64 critical
technological domains, including defense, space, energy, environment, artificial

In 1978, Massachusetts took a risk and made an $8.5 million investment into one of the earliest technology-based economic development (TBED) initiatives in the world. The commonwealth, among the states hard-hit by the global manufacturing restructuring underway at the time, which led to the deep recession of the early 80s, knew it needed to try something different to restore its economy and its long-term competitiveness.

The U.S. Department of Commerce recently announced that the agency formerly known as the U.S. AI Safety Institute has been renamed the Center for AI Standards and Innovation (CAISI)The center’s priority focus areas also have been adjusted so that CAISI can serve as industry’s primary point of contact within the U.S. Government to facilitate testing and collaborative research. According to the Commerce announcement, CAISI will:

The U.S. Small Business Administration posted a notice in the June 9, 2025, Federal Register of SBA’s intent to establish a Manufacturing in America Advisory Committee to “provide strategic guidance, advice, and recommendations to the U.S. government and relevant stakeholders on matters related to growth, supply chain resilience, and innovation of small manufacturing businesses across the country. The committee will act as the collaborative body to ensure the sector's needs, challenges, and opportunities are addressed.