One of the top perennial concerns of America’s manufacturing and business communities relates to the workforce. The main issues may vary year to year; examples include too few workers available, skill mismatch, poor work habits or preparedness because of non-work issues such as basic education attainment, drug use, prison records or lack of work ethic.

A recently published InfoChart from the National Center for Science and Engineering Statistics (NCSES) presents an annotated walk through federal R&D obligations from FY 1951 through 2024, explaining key events influencing key moments in the surges and downswings along the nation’s path to supporting discovery, research, development and innovation. The data is presented in constant 2017 dollars. 

In 1978, Massachusetts took a risk and made an $8.5 million investment into one of the earliest technology-based economic development (TBED) initiatives in the world. The commonwealth, among the states hard-hit by the global manufacturing restructuring underway at the time, which led to the deep recession of the early 80s, knew it needed to try something different to restore its economy and its long-term competitiveness.

The U.S. Department of Commerce recently announced that the agency formerly known as the U.S. AI Safety Institute has been renamed the Center for AI Standards and Innovation (CAISI)The center’s priority focus areas also have been adjusted so that CAISI can serve as industry’s primary point of contact within the U.S. Government to facilitate testing and collaborative research. According to the Commerce announcement, CAISI will:

The U.S. Small Business Administration posted a notice in the June 9, 2025, Federal Register of SBA’s intent to establish a Manufacturing in America Advisory Committee to “provide strategic guidance, advice, and recommendations to the U.S. government and relevant stakeholders on matters related to growth, supply chain resilience, and innovation of small manufacturing businesses across the country. The committee will act as the collaborative body to ensure the sector's needs, challenges, and opportunities are addressed.

With Q1 2025 venture capital (VC) data stabilized and reports coming out on investment activity, it is a good time to review 2025 VC investment from a TBED perspective. Many published reports on VC activity include deals at the top end of the size range that—with individual transactions now reaching- billions of dollars—can swing some of the metrics and mask the underlying nuances facing smaller companies and markets. While investment levels are trending up, the totals are driven by mega deals and AI companies.

Many SSTI members will attend the annual BIO International Convention, which will be held this year in Boston from June 16 to 19. There, they join a cohort of organizations with various connections to the life sciences, including contract research and manufacturing companies, academic centers, "big" pharma, "little" pharma, and foreign nations representing their life sciences efforts. 

In fiscal year (FY) 2023, federal obligations for science and engineering (S&E) to universities and colleges totaled $49 billion—$29 billion more than FY 2000, and a 10% increase from the prior year. The growth is less rapid when adjusted for inflation (2017 USD), with just over $40 billion in real obligations in FY 2023, a 5% increase over the year prior and $12.6 billion (or 46%) increase over the FY 2000 value.

The Australian Strategic Policy Institute’s (ASPI) report, ASPI’s two-decade Critical
Technology Tracker: The rewards of long-term research investment, aims to identify
which countries and institutions are leading in high-impact research across 64 critical
technological domains, including defense, space, energy, environment, artificial