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NSF selects 15 finalists to advance to the next round of its second Regional Innovation Engines competition

Thursday, September 18, 2025
  • Read more about NSF selects 15 finalists to advance to the next round of its second Regional Innovation Engines competition

Federal government wants patent rights? Budget bills see action

Thursday, September 11, 2025
Large federal slice of patent pie looming? In an exclusive interview with Mike Allen on The Axios Show, U.S. Commerce Secretary Howard Lutnick floated the idea that the federal government should receive “half the benefits” of federal R&D, referring to a direct share of the financial returns from patents stemming from R&D funded by the federal government.
  • Read more about Federal government wants patent rights? Budget bills see action

Congress likely to punt on SBIR reauthorization

Wednesday, September 10, 2025

As the end of the fiscal year approaches, Congress is again at a critical juncture in reauthorizing the SBIR and STTR programs.

As the end of the fiscal year approaches, Congress is again at a critical juncture in reauthorizing the SBIR and STTR programs. With only two hearings (one each in the House and Senate Small Business Committees) held so far this year on the topic, Congressman Roger Williams (R-TX), Chairman of the House Committee on Small Business, introduced H.R.5100 on September 3 to extend the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) programs, set to expire on September 30, 2025, for one year, “as is.” The bill passed out of committee on September 10.
  • Read more about Congress likely to punt on SBIR reauthorization

Biotech VC funding points to early-stage funding gaps

Wednesday, September 10, 2025

As attention-grabbing as AI might be for the media and large investors (see previous SSTI analysis of AI investment), economic growth through innovation in life sciences and biotechnology is a priority for many state and regional TBED initiatives.  The venture capital market recognizes that as well.

As attention-grabbing as AI might be for the media and large investors (see previous SSTI analysis of AI investment), economic growth through innovation in life sciences and biotechnology is a priority for many state and regional TBED initiatives. The venture capital market recognizes that as well. In fact, Pitchbook estimates the broad biotechnology sector (comprising life science, pharma, health care, devices, etc.) captured 14% of all deals so far in 2025, making it the second largest investment group after info tech this year to date.
  • Read more about Biotech VC funding points to early-stage funding gaps

Recent research: Does larger size make a firm more innovative?

Wednesday, September 10, 2025

Conventional TBED wisdom for decades has been that small businesses generate more innovation in the United States. All big tech companies started as scrappy little companies in their respective eras of IT’s rapid growth. But there remains a long-running debate about whether large firms with financial resources and R&D capacity have an innovation advantage over smaller but more agile firms.

Conventional TBED wisdom for decades has been that small businesses generate more innovation in the United States. All big tech companies started as scrappy little companies in their respective eras of IT’s rapid growth. But there remains a long-running debate about whether large firms with financial resources and R&D capacity have an innovation advantage over smaller but more agile firms. Understanding the arguments for each side is important for policymakers and business leaders as they seek ways to support small and medium-sized enterprises and leverage the innovative capacity of larger corporations. In their paper, Firm Size and Innovative Performance: A Meta-Analysis Across 25 Years of Evidence, Federico Bachmann and Rodrigo Ezequiel Kataishi provide a comprehensive meta-analysis that synthesizes 25 years of research to clarify this relationship.  

  • Read more about Recent research: Does larger size make a firm more innovative?

Philanthropy is unlikely to fill the gap left by decreased government funding

Wednesday, September 10, 2025

As federal funding for science research decreases, it may be tempting to think that philanthropy might be able to fill the gap. However, a recent study from the Science Philanthropy Alliance illustrates that it cannot replace the robust funds that government allocation once contributed.  

  • Read more about Philanthropy is unlikely to fill the gap left by decreased government funding

Useful Stats: Examining county-level employment and establishments by sector

Wednesday, September 10, 2025

Understanding the composition of local economies requires looking beyond broad statewide or national trends. County-level data reveals the unique mix, or lack thereof, of industries and businesses in each area. Policy makers, by identifying which sectors drive employment and business activity within a locality, can influence the impact and design of regional innovation strategies to reflect local realities and potential.  

Understanding the composition of local economies requires looking beyond broad statewide or national trends. County-level data reveals the unique mix, or lack thereof, of industries and businesses in each area. Policy makers, by identifying which sectors drive employment and business activity within a locality, can influence the impact and design of regional innovation strategies to reflect local realities and potential.  

The U.S. Bureau of Labor Statistics’ Quarterly Census of Employment and Wages (QCEW) allows examination of county-level employment and establishment counts across all private sectors at the 2-digit NAICS level. In this article, SSTI uses annualized private sector data for all provided 2-digit NAICS sectors at the county level for 2015 and 2024.

  • Read more about Useful Stats: Examining county-level employment and establishments by sector

Private sources step up to fund telescope that rivals the defunct Arecibo telescope

Wednesday, September 10, 2025
  • Read more about Private sources step up to fund telescope that rivals the defunct Arecibo telescope

Q2 investment trends continue the shift to fewer but larger deals

Wednesday, August 27, 2025
  • Read more about Q2 investment trends continue the shift to fewer but larger deals

The Trump administration proposes significant changes in consolidated workforce plan

Wednesday, August 27, 2025
  • Read more about The Trump administration proposes significant changes in consolidated workforce plan

Recent Research: How much does place matter for scientific output?

Wednesday, August 27, 2025
  • Read more about Recent Research: How much does place matter for scientific output?

Recent research: Tulsa Remote study shows strong economic returns

Wednesday, August 27, 2025

To grow their local populations and STEM workforce, communities across the country are experimenting with resident/worker attraction programs, as we have previously covered. But how effective are these programs? A recent study from the W.E. Upjohn Institute for Employment Research offers new insights by analyzing Tulsa Remote’s track record from its inception in 2018 to 2023.  

  • Read more about Recent research: Tulsa Remote study shows strong economic returns

Employee use and perceived impacts on their competence may be behind the slow AI adoption in the workplace

Wednesday, August 27, 2025
  • Read more about Employee use and perceived impacts on their competence may be behind the slow AI adoption in the workplace

Accelerating innovation is a key pillar of America’s AI Action Plan

Thursday, August 14, 2025
  • Read more about Accelerating innovation is a key pillar of America’s AI Action Plan

Educational Opportunities

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Executive Order aims to reorganize federal grantmaking

Thursday, August 14, 2025
A recent executive order from the White House aims to centralize federal grantmaking. This revamping of the grantmaking process would affect how decisions are made regarding the distribution of billions of dollars in research grants and have a significant impact on research universities.  While the order notes, “nothing in this order shall be construed to discourage or prevent the use of peer review methods,” it sidelines the peer review process with the disclaimer, “provided that peer review recommendations remain advisory” to the senior appointees. These senior appointees are directed to “use their independent judgment.”  All final grant award decisions across all agencies are to be made by political appointees. 
  • Read more about Executive Order aims to reorganize federal grantmaking

EDA has cancelled the FY 24 Build to Scale Competition

Thursday, August 14, 2025
  • Read more about EDA has cancelled the FY 24 Build to Scale Competition

DOE plans to offer $1B for battery and critical minerals technology advancement

Thursday, August 14, 2025
  • Read more about DOE plans to offer $1B for battery and critical minerals technology advancement

Seven universities receive NSF Regional Resilience Innovation Incubator (R2I2) funding

Thursday, August 14, 2025
NSF’s Regional Resilience Innovation Incubator (R2I2) project has awarded Phase 1 funding to six teams, each addressing specific regional climate challenges and demonstrating solutions. The award includes funding for a seventh team to create the R2I2 National Office, which will support the collective and coordinated implementation of R2I2 award activities.
  • Read more about Seven universities receive NSF Regional Resilience Innovation Incubator (R2I2) funding

Examining the geographic concentration of VC investment in AI

Thursday, August 14, 2025
The dominance of artificial intelligence (AI) investments in venture capital (VC) has been a consistent storyline in the first half of 2025. PitchBook, Carta, Crunchbase, and many others have all pointed to the significant portion of investment dollars and deals flowing to AI companies. With the volume of companies, deals, and dollars involved, it is more than a spike in the usual cyclic nature of  VC investment.   As SSTI wrote in our review of Q1 venture capital investment activity, VC has been concentrating in larger deals. With market trends and mega deals in AI so well documented, we explore investment concentration from  deal size and geographic perspectives. As with prior analyses, we focus on deal sizes more relevant to TBED initiatives to help regional innovation leaders identify where they might find opportunities, face challenges, or set priorities in such a dynamic environment. Excluding the largest deals from our analysis appears to be increasing important, considering  PitchBook’s findings that just ten companies accounted for 41% of all venture dollars so far this year.  
  • Read more about Examining the geographic concentration of VC investment in AI

Recent research: Who benefits from state workforce development grants?

Thursday, August 14, 2025
  • Read more about Recent research: Who benefits from state workforce development grants?

Modest Tech Hubs funding included in FY 2026 appropriation bills

Thursday, July 31, 2025

House and Senate subcommittees with oversight for Commerce, State and Justice appropriations differ on funding recommendations for the EDA Regional Technology and Innovation Hubs program, commonly referred to as Tech Hubs. While any funding in a tight budget environment is good, the $50 million in the House version of the CJS bill or the Senate subcommittee’s $60 million is far short of Congress’s original vision for the Tech Hubs, authorized at $10 billion over ten years.

  • Read more about Modest Tech Hubs funding included in FY 2026 appropriation bills

House subcommittee zeroes out FAST in 2026

Thursday, July 31, 2025

The Financial Services and General Government (FSGG) subcommittee of House Appropriations has turned against the Federal and State Technology (FAST) Partnership in its budget recommendations for the Small Business Administration, zeroing out the only program that provides funds to help states level the competitive field of applicants for the SBIR/STTR program. While the FAST funds were decreased from the $9 million enacted in FY2024, the SBDC line item received a $10 million increase in the FSGG appropriations proposal.

  • Read more about House subcommittee zeroes out FAST in 2026

Senate, House offer sharp differences in NSF’s FY 26 budget prospects

Thursday, July 31, 2025

The nearly status quo nature of the FY 2026 budget of $9.0 billion for the National Science Foundation advanced by the Senate Appropriations Committee stands in striking contrast to the Administration’s $3.9 billion request. House appropriations, meanwhile, appropriated $7.0 billion for NSF, a reduction of $2.06 billion or 23% from the FY 2025 enacted level.

  • Read more about Senate, House offer sharp differences in NSF’s FY 26 budget prospects

FY 26 budget for EDA’s Build to Scale program level at $50M—so far

Thursday, July 31, 2025

In perhaps the most difficult budget season of the last 25 years, where the President’s budget has proposed eliminating funding for scores of programs, both the House and Senate subcommittees with budget oversight for the Economic Development Administration (EDA) have proposed continuation funding of $50 million for FY2026 for the popular Build 2 Scale (B2S) program—referred to as the Regional Innovation Program Grants in budget language.

  • Read more about FY 26 budget for EDA’s Build to Scale program level at $50M—so far

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Recent news from the SSTI Digest

Reauthorization of EDA’s popular Build to Scale program introduced

Thursday, May 21, 2026
The bipartisan Build to Scale Reauthorization Act of 2026 was introduced on May 15 by Congresswoman Haley Stevens (MI-11) and Rep. Jim Baird (R-IN), along with several co-sponsors. Additionally, more than sixty organizations and associations in 25 states endorsed the bill, which is designed to help Americans move new products, technologies, and medical inventions to market faster.
b2s

Nonprofit Venture Development Organizations: what they are and why the approach matters

Thursday, May 21, 2026
Over the past 25 years, SSTI has seen a successful model emerge for supporting regional innovation-driven economies that deserves more attention from the TBED community. Successful Venture Development Organizations (VDOs) bring the entrepreneurial mindset of an innovation startup to regional economic growth strategies. VDOs simultaneously deliver multiple value propositions to their target service areas.
venture dev orgs

Connecting companies to research assets faster: the Tennessee Innovation Exchange model

Thursday, May 21, 2026
The Tennessee Innovation Exchange (TNIX) is a statewide initiative designed to make it easier for companies, entrepreneurs, and investors to connect with university research expertise across Tennessee. In this recent TBED Community of Practice webinar, speakers Chuck Layne of LaunchTN and Tom Kissane of Halo Sciences explained how they partnered with six research universities to build a shared digital platform that supports university-industry collaboration and commercialization.
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