VC data highlights what types of deals are slowing early-stage investment activity
Long concentrated geographically, venture capital also is growing more concentrated in a small number of larger deals, as SSTI has reported in recent Digest issues. In fact, deals under $100 million—not a small figure in itself—have fallen by 71% according to SSTI’s analysis of PitchBook data. Even more troubling is evidence showing deals under $100 million are moving to later-stage investment and away from early-stage companies.
Group calls for cross-region action to address semiconductor labor shortages
For the United States to achieve greater security in chip manufacturing, the critical sector requires a much larger, better trained workforce.
Research provides insights into how employees are using AI and their concerns about the technology
If you’re leading a knowledge work[1] organization and considering introducing generative artificial intelligence into your workflow, it likely would be helpful to know how its use may impact the day-to-day aspects of your team’s work, and the potential risks involved.
TBED101: Distinguishing critical and emerging technologies in policy
Note: TBED101 is a new, occasional series for Digest readers visiting and revisiting fundamental topics for nurturing strong regional innovation economies. SSTI is introducing this series, with EDA support, as the field has entered one of its most significant periods of disruption and change in its 45-year history.
With $93M injection, New Mexico boosts its support for TBED
The list of technology-based economic development initiatives within the newly created Technology and Innovation Office of the New Mexico Economic Development Department covers the spectrum of critical policy aspects required for a strong state innovation economy: increasing R&D, business incubation, targeted emerging technologies and strong existing assets, startup capital, venture development, and innovation talent development and recruitment.
Innovation Advocacy Council convening for update on DC budget activities affecting TBED
On June 3, SSTI will host a webinar exclusively for Innovation Advocacy Council members to receive an in-depth update on many of the confusing factors in play in the federal policy and budget environments—the key factors influencing the future of your state, regional and university TBED strategies. IAC partners at Van Scoyoc & Associates will be on hand to provide the latest news from the Hill and answer questions to help make sense of any new developments.
Improving public-private innovation finance: SSTI launches a new community of practice
Tuesday, July 1 | 3:00 p.m. EST
Whether your region is just beginning to address market failures in risk capital availability and performance for innovation-centered companies or your current efforts could use a refreshing check-in among peers, please plan to join us for the kick-off of our Innovation Finance Community of Practice Series.
MassVentures report reveals the impact sustained, smart public innovation finance can have
In 1978, Massachusetts took a risk and made an $8.5 million investment into one of the earliest technology-based economic development (TBED) initiatives in the world. The commonwealth, among the states hard-hit by the global manufacturing restructuring underway at the time, which led to the deep recession of the early 80s, knew it needed to try something different to restore its economy and its long-term competitiveness.
The U.S. AI Safety Institute has been renamed the Center for AI Standards and Innovation
The U.S. Department of Commerce recently announced that the agency formerly known as the U.S. AI Safety Institute has been renamed the Center for AI Standards and Innovation (CAISI). The center’s priority focus areas also have been adjusted so that CAISI can serve as industry’s primary point of contact within the U.S. Government to facilitate testing and collaborative research. According to the Commerce announcement, CAISI will:
SBA is possibly ramping up manufacturing support with a new advisory committee
The U.S. Small Business Administration posted a notice in the June 9, 2025, Federal Register of SBA’s intent to establish a Manufacturing in America Advisory Committee to “provide strategic guidance, advice, and recommendations to the U.S. government and relevant stakeholders on matters related to growth, supply chain resilience, and innovation of small manufacturing businesses across the country. The committee will act as the collaborative body to ensure the sector's needs, challenges, and opportunities are addressed.
SSTI review of Q1 2025 VC investment sees pipeline problems brewing for regional TBED goals
With Q1 2025 venture capital (VC) data stabilized and reports coming out on investment activity, it is a good time to review 2025 VC investment from a TBED perspective. Many published reports on VC activity include deals at the top end of the size range that—with individual transactions now reaching- billions of dollars—can swing some of the metrics and mask the underlying nuances facing smaller companies and markets. While investment levels are trending up, the totals are driven by mega deals and AI companies.
How organizations use BIO to advance their TBED goals
Many SSTI members will attend the annual BIO International Convention, which will be held this year in Boston from June 16 to 19. There, they join a cohort of organizations with various connections to the life sciences, including contract research and manufacturing companies, academic centers, "big" pharma, "little" pharma, and foreign nations representing their life sciences efforts.
Federal obligations for higher-ed S&E near an inflation-adjusted all-time high in 2023
In fiscal year (FY) 2023, federal obligations for science and engineering (S&E) to universities and colleges totaled $49 billion—$29 billion more than FY 2000, and a 10% increase from the prior year. The growth is less rapid when adjusted for inflation (2017 USD), with just over $40 billion in real obligations in FY 2023, a 5% increase over the year prior and $12.6 billion (or 46%) increase over the FY 2000 value.
Recent Research: ASPI Report says U.S. cedes lead in critical technologies research
The Australian Strategic Policy Institute’s (ASPI) report, ASPI’s two-decade Critical
Technology Tracker: The rewards of long-term research investment, aims to identify
which countries and institutions are leading in high-impact research across 64 critical
technological domains, including defense, space, energy, environment, artificial
National Science Foundation requests input for potential updates to its key technology focus areas
The U.S. National Science Foundation (NSF) is requesting information from the public to help shape potential future updates to its Key Technology Focus Areas (KTFAs). NSF’s KTFAs directly influence and shape innovation- and economic development-related programs.
SSTI updates key technology area investment data tool through 2025 H1
SSTI has updated its Key Technology Area Investment Data Tool with new and refreshed data spanning January 1, 2013, through June 30, 2025. The tool comprises two interactive visuals and uses Pitchbook technology verticals selected to align with many of the key technology focus areas (KTFAs) defined in the CHIPS and Science Act of 2022 (CHIPS).
Recent Research: SBIR companies support critical national needs
Over the past 40 years, many people involved in SBIR and empirical analysts in the research, finance, and technology sectors have said SBIR awardees, as a group, are uniquely important for America’s innovation goals.
What the tax code changes could mean for TBED activities
Please note: this article is not intended as a comprehensive review of Public Law No. 119-21, nor should our reading of the law be treated as tax or legal advice.
NSF selects 29 semifinalists in the second NSF Regional Innovation Engines competition
The overlap between applicants and recipients of the three large regional innovation approaches attempted by the federal government so far continues with the July 9, 2025, NSF narrowing of the field for the second NSF Regional Innovation Engines competition to 29 semifinalists across the country.